Aims. There are two treatment modalities for early gastric cancer (EGC)ââ?¬â?surgery and endoscopic submucosal dissection\n(ESD). We aimed to compare the safety and efficacy of ESD with surgery. Method. The article was performed by searching\nPubMed databases. Data were extracted using predefined form and odds ratios (OR) with 95% confidence intervals (CI)\ncalculated and P value. Results. 13 studies were identified. The incidence of perforation in two groups was different [OR = 6.18\n(95% CI: 1.37ââ?¬â??27.98), P = 0 02]. The prevalences of synchronous and metachronous cancer in the ESD group were higher\nthan those in the surgery group [OR = 8.52 (95% CI: 1.99ââ?¬â??36.56), P = 0.004 and OR= 7.15 (95% CI: 2.95ââ?¬â??17.32), P < 0 0001].\nThe recurrence and complete resection rates were different [OR = 6.93 (95% CI: 2.83ââ?¬â??16.96), P < 0 0001 and OR= 0.32 (95% CI:\n0.20ââ?¬â??0.52), P < 0 00001]. Compared with the surgery group, the hospital stay was shorter [IV = âË?â??7.15 (95% CI: âË?â??9.08ââ?¬â??5.22),\nP < 0 00001], the adverse event rate was lower, and the quality of life (QOL) was better in the ESD group. The difference\nof bleeding was not found. Conclusion. ESD appears to be preferable for EGC, due to a lower rate of adverse events,\nshorter hospital stay, cheaper cost, and higher QOL.
Loading....